Episodic falling syndrome (EFS) in Cavalier King Charles spaniels is a canine paroxysmal hypertonicity disorder. Episodes begin between fourteen weeks and four years of age and are triggered by exercise, stress, apprehension or excitement. Episodes are characterized by progressive hypertonicity throughout the thoracic and pelvic limbs, which can lead to immobilization and collapse. Other clinical signs may include facial muscle stiffness, stumbling, a 'bunny-hopping' gait and arching of the back.
Inheritance: autosomal recessive - read more
Mutation: BCAN gene
Genetic test: The method used for testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. Testing can be done at any age.
Disease control: read more
Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.