Primary open angle glaucoma (POAG)

Primary open angle glaucoma (POAG) is a hereditary disease which can be tested with a DNA test. Glaucomas represent a group of diseases characterized by increased intraocular pressure, which causes retinal and optic disk destruction. Primary open angle glaucoma (POAG) in Beagles is an inherited condition with typically increased eye pressure in both eyes. Symptoms become detectable between 8 and 16 months of age. As the pressure in the eye increases, the eyeball increases in size and becomes painful. Symptoms include sudden onset of pain, redness, tearing, squinting and blinking of the eye. If POAG is left untreated, increased pressure in the eye leads to optic nerve damage and gradual loss of vision. Most dogs exhibit luxation of the lens by 2,5 years of age. 

Inheritance: autosomal recessive - read more

Mutation: ADAMTS10 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age. 

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.

Price:

42.70 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
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