Progressive retinal atrophy (NECAP1-PRA) is a DNA test for Hereditary diseases. Canine progressive retinal atrophies (PRA) are genetically heterogeneous diseases caused by several mutations and affects more than 100 dog breeds. The hereditary disease primarily affects photoreceptors initially leading to night blindness. As the hereditary disease progresses impairment of daylight vision and eventually complete blindness occurs. In Giant Schnauzer, the clinical symptoms occur approximately at four years of age. A missense variant in NECAP1 gene has been identified, suggesting a novel form of PRA in Giant Schnauzer. The EVG has the best DNA test for dogs with a DNA test kit that makes it easy to use.
Inheritance: autosomal recessive - read more
Mutation: NECAP1 gene
Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.
Disease control: read more
Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.