Progressive retinal atrophy (PRA) in dogs is a group of genetically heterogeneous inherited retinal disorders characterized by progressive degeneration and cell death of photoreceptors. GR-PRA1 is a late onset disease (usually at 6 - 7 year) with some individual variation in age of onset, and is inherited in an autosomal recessive manner. Until now, three different mutations were found to cause progressive retinal atrophy (PRA) in Golden Retriever breed: PRA-PRCD, GR-PRA1 and GR-PRA2.
Inheritance: autosomal recessive - read more
Mutation: SLC4A3 gene
Genetic test: The method used for testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. Testing can be done at any age.
Disease control: read more
Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.