Inflammatory Pulmonary Disease (IPD) is a hereditary disease that can be tested with a DNA test.  Inflammatory Pulmonary Disease (IPD) is an inherited form of recurrent pneumonia in Collies with similar clinical presentation as primary ciliary dyskinesia (PCD). Typical clinical signs include recurrent foamy vomiting, shallow breathing, coughing, increased breathing sounds, nasal discharge and fever. Clinical signs can start at a few days of age. Dogs usually respond to therapy with antibiotics and secretolytics but usually a relapse occurs quickly. this hereditary disease shows autosomal recessive mode of inheritance.  

Inheritance: autosomal recessive - read more

Mutation: upstream of AKNA gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age. 

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.